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Dual luciferase assays were performed for relative luciferase activity in cell groups co-transfected with the pmiRGLO plasmids containing wild type (wt) or mutant type (mt) of MALAT1 (MALAT1-wt, MALAT1-mt), siRNA targeting MALAT1(si-MALAT1) miR-155-5p inhibitor or their control was transfected into KGN cells using Lipofectamine 2000

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Recognizing glucose metabolism reprogramming as a pivotal therapeutic target in oncology, we emphasize the indispensable role of nanomedicine in overcoming persistent barriers to advance tumor-selective metabolic intervention, thereby elevating treatment efficacy and accelerating the clinical translation of precision nanotherapeutics

The fat is then stored in the body, and the acetate is used for energy