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Competing interests None declared

For many practitioners and users, the optimal approach involves strategic selection based on current needsor even combination protocols that leverage the unique benefits of each delivery method at different times of day or phases of treatment

Bioidentical progesterone is widely used to counterbalance excess estrogen and is generally considered appropriate when prescribed and monitored by a qualified provider

In the case of KBP-089, a dual amylin and CTR agonist, the additivity of DACRAs and GLP-1 RA in improved insulin sensitivity and body weight reduction was demonstrated in the ratanimal model [119, 120]

A key cofactor for cellular energy production that supports mitochondrial function and antioxidant defense