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In, Kaplowitz N, DeLeve LD, eds

2021;106(3)(suppl 1):912-921

Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes

Heart failure, especially with reduced ejection fraction (HFrEF), is characterized by impaired pump function usually following myocardial injury, accompanied by neurohormonal activation and pathological remodeling (fibrosis, hypertrophy)