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Direct mechanisms of tirzepatide on cardiovascular health Although the precise mechanism by which tirzepatide could benefit HF is not known, several potential pathways have been suggested: Anti-inflammatory effects Patients with T2DM experience increased levels of hyperinsulinemia, hyperglycemia, and insulin resistance

doi: 10.4049/jimmunol.1900658 118 FuGGuyCSChapmanNMPalaciosGWeiJZhouPet al

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Philly-area bariatric surgery programs face upheaval amid growing GLP-1 use for weight loss Ozempic and other GLP-1s have cut into the volume of bariatric surgeries in Philadelphia and nationally, but surgeons say the need for the procedures will continue