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While neither liraglutide nor semaglutide is FDA-approved for cardiovascular protection, research suggests both may help lower the risk of major heart-related events like heart attack, stroke, or cardiovascular death in people with type 2 diabetes

Also, headaches are more common in the treatment group (ROSE-010 at 300 g) than in the placebo group

The FDA has approved certain medications (Victoza, Ozempic, Trulicity) for cardiovascular risk reduction in patients with established cardiovascular disease and type 2 diabetes, and Wegovy for cardiovascular risk reduction in adults with established cardiovascular disease who have overweight or obesity

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The expression correlation between genes was calculated by Pearsons correlation coefficient, and a network diagram was constructed using cytoscape