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Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress
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Other oxidative or injury-related biomarkers (MDA/TBARS, SOD, SH, CK, IL-6) showed no significant changes, likely reflecting assay variability, insufficient dosing, or limited statistical power
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