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Furthermore, researchers have found that the gene expression of vasoactive intestinal peptide (VIP)-expressing interneurons is downregulated in individuals with ASD compared to healthy controls, with the most significant differential expression, suggesting potential dysfunction of VIP interneurons in people with ASD ( In addition, Reelin is an extracellular matrix glycoprotein closely related to neural development, which is involved in the regulation of neuronal migration, synaptic plasticity and neural network formation (36).Reelin affects the migration and synaptic integration of GABAergic interneurons by regulating disabled-1 (Dab1) and PI3K/AKT pathways

Funding This work was supported by the State Committee of Science RA (N 10-14/23-I/YSMU and 20TTCG-3A012) and the EU-funded H2020 COBRAIN project (857600)

With low DAO production and hyperactive mast cells constantly dumping endogenous histamine into the system, the patient's "histamine bucket" quickly overflows

61/710,515, filed on Oct

In particular, mechanism of obesity and diabetes mediated CKD and emerging dietary therapies for MetS associated CKD will be discussed