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Different studies reported the effects of different parts of okra on alloxan-induced diabetic rats and showed that there was a significant reduction in the blood glucose level and glycated hemoglobin and an improvement in the lipid profile compared with the diabetic nontreated control rats and comparable with the metformin-positive control group [95,96]

There is accumulating evidence for diverse changes in molecular expression of reactive astrocytes in different types and different severities of tissue pathology, 62,65,68,69 but there is not yet a good synthesis of how molecular, metabolic, 87 structural, and functional changes relate to one another to generate precisely definable phenotypes

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