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Research has suggested that AHK-Cu may participate in cellular signaling and regulation processes, with particular interest in vascular endothelial cells and fibroblasts

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Authors contributions Concept and design (KK, YS), acquisition of data (KK, NAE), drafting of the manuscript (KK, NAE), critical revision of the manuscript for important intellectual content (KK, NAE, YS), and study supervision (YS)

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We further elucidate how aging, environmental toxicants, lifestyle choices, and pathological conditions such as cystic ovaries and endometriosis exacerbate oxidative damage, thereby severely compromising meiotic competence and embryonic development