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GLP-1 medications make it easier to lose weight by curbing appetite, reducing cravings, and slowing stomach emptying

J Clin Invest (2001) 107(5):58593.10.1172/JCI11476 118 HeazlewoodCKCookMCEriRPriceGRTauroSBTaupinDet alAberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

As our understanding of HFpEF evolves, GLP-1RAs have the potential to become a cornerstone of therapy, addressing the multifactorial nature of this condition and improving outcomes in a challenging patient population

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If results are weak into the remodelling phase and starting dose was sub-3.2 mg, a dose increase and protocol modification may be warranted