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Effective management of diarrhoea whilst taking Rybelsus involves both non-pharmacological and pharmacological strategies

Firstly, it needs to be reduced to Fe 2+ by gastric acid or the action of cytochrome b heme reductase 1 (duodenal cytochrome b, DCYTB), before it can be transported into the small intestinal villus cells by divalent cation transporter 1 (DMT1)

Around 29% of adults in the UK are living with obesity - a condition associated with cardiovascular disease, type-2 diabetes and certain cancers, and thought to contribute to over 30,000 deaths a year

However, lifestyle changes are difficult to maintain over the long term [9]

It fell a further 3% on Wednesday