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It works by activating two hormone receptors, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which together help regulate blood sugar, appetite, and digestion

10.1371/journal.pone.0165130 170 ZhangY.FavaG

Staying hydrated with water, electrolyte drinks, or clear broths helps prevent dehydration from vomiting and supports digestive function

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It is contraindicated in patients with hypersensitivity to tirzepatide or any of the excipients in the formulation