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GI AEs consistent with class Mechanism: Dual GLP-1 + glucagon receptor agonism enhances energy expenditure and metabolic balance, offering a next-gen alternative to GLP-1 monotherapy

Each eating occasion targets 200-300 calories

Complications , whilst uncommon, include ovarian torsion (twisting of the ovary, cutting off blood supplya surgical emergency), cyst rupture causing acute pain and internal bleeding, and rarely, malignant transformation in certain cyst types, particularly in postmenopausal women

When the results dont match the effort and expense, many choose to stop

Biotransformation can temporarily increase reactivity