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GLP-1 RAs, synthetic analogues of endogenous GLP-1, stimulate insulin secretion while inhibiting glucagon release, with additional benefits in gastric emptying and appetite suppression [8, 9]

Many of these positive and negative associations make biological sense based on more basic science, lending credibility to their plausibility

It is often associated with hypothyroidism

The benefits can last several weeks, depending on your bodys metabolism and lifestyle

One final consideration is that as more states establish upper payment limit (UPL) setting authority either for prescription drug affordability boards or other similar entities, it becomes increasingly possible that GLP-1s could be subject to review and UPLs across various states