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Statins are inhibitors of the MVA pathway, inhibit cholesterol synthesis [52], and are the most common lipid-lowering drugs used in clinical practice [53]

While GLP-1RAs are guideline-recommended for CVD risk reduction in T2D, their impact on SAa potent CVD risk multiplierremains poorly understood

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Insurers typically request BMI documentation, evidence of weight-related medical conditions, lifestyle program participation, and sometimes prior treatment history before approving coverage

doi: 10.1016/j.ymben.2020.08.015 23 HayakawaM.HiraT.NakamuraM.IidaT.KishimotoY.HaraH