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Early calorie restriction depletes glycogen stores, releasing bound water and electrolytes such as sodium and potassium, which can trigger dizziness and fatigue

10.3390/molecules23102598 80 TatipamulaV

The majority of the existing evidence is derived from preclinical animal models, with limited data available from human studies

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There have been no human pharmacokinetic or metabolic studies, to show potential risk factors or side effects to date