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El Mounjaro y el Zepbound funcionan de forma similar, pero utilizan tirzepatida (en lugar de semaglutida) para simular tanto la GLP-1 como una segunda hormona, la GIP

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Mutation of cysteine 26 alone or in combination with mutation of other cysteines increases GLRX deglutathionylation activity We next investigated the deglutathionylating activity of WT GLRX or GLRX Cys-Ser mutants using diE-GSSG (Fig