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The only reimbursed option is liraglutide 3 mg, making it a relevant comparator in this study

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In line with these findings, deletion of GLP-1Rs in paired-like homeobox 2b (PHOX2B)-expressing neurons, which mark all vagal sensory afferents, minimally affects the acute appetite suppressing effects of exendin-4 and only partially prevents the weight loss caused by chronic treatment with the GLP-1R agonist dulaglutide [35]

Ans: On average, patients lose about 5% to 10% of their body weight with a short-term course of phentermine