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A thorough pre-treatment conversation should include baseline biomarker assessment, rule-out of reversible causes of hair loss (nutritional deficiency, thyroid disease, hormonal imbalance), and realistic expectations about evidence

Furthermore, the review identifies underexplored research gaps such as tissue-specific senescence heterogeneity, biomarker-driven patient selection, and advanced delivery systems, that, if addressed, could substantially advance both scientific knowledge and clinical application in geroscience