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75% of patients who initiate a diabetes-indicated GLP-1 have filled metformin or another diabetes treatment prior to initiation, while the majority of weight-loss indicated GLP-1 initiators have had no prior fills of any diabetes products

Because at those scales when we have these things like, oh, the tendon doesnt work as well, or oh this doesnt work as well, those get magnified, bone mass maybe is affected, all of those things are then going to get magnified by the number of people who are on it and the number of these kind of side effects are gonna be much, much worse

Capuccio S, Scilletta S, La Rocca F, Miano N, Di Marco M, Bosco G, et al

These typically improve over time, especially with gradual dose escalation

Eventually, it leads to uptake of glucose by the body cells and decreasing the level in the blood