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Among the anorexigenic peptides, the first recognized inhibitor of food intake in rodents (36) and then in humans (37-40) was cholecystokinin (CCK), the product of duodeno-jejunal endocrine I cells acting via CCK1 receptors on vagal afferent nerves

For example, in 2021, Employers Health clients that cover AOMs and have prior authorizations spent $0.85 PMPM on obesity products, while those without any restrictions spent $1.08 PMPM

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