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Conclusions Across preclinical and translational studies, GLP-1RAs have emerged as promising candidates for NDD therapy, consistently modulating convergent mechanisms of pathology: IR, mitochondrial dysfunction, oxidative stress, proteostasis failure, synaptic loss, and neuroinflammation

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Delta Sleep-Inducing Peptide (DSIP) is a neuropeptide that influences several physiological processes, primarily around sleep regulation

During this period, typical weight loss ranges from 2 to 5 percent of baseline body weight