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Modulation of skeletal muscle antioxidant defense by exercise: role of redox signaling

Ipamorelin and GHRH produce synergistic GH release when co-administered , with the combined response substantially exceeding the sum of individual responses through complementary Gq/11 and Gs signalling pathway interactions in somatotrophs, identical in mechanism to the GHRH-GHRP-6 and GHRH-GHRP-2 synergy documented for non-selective GH secretagogues but without prolactin and cortisol co-stimulation confounding the combined endocrine response

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View Source Physiology & behavior The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism 2024 DOI: 10.1016/j.physbeh.2024.114644 PMID: 39043357 Lu Z, Ngan MP, Liu JYH, et al