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Without a loading dose, it would take months to achieve a therapeutic effect, which is likely clinically unacceptable
In addition to its direct antioxidant functions, glutathione (GSH) contributes to the regeneration of other antioxidants, including vitamins C and E, and is involved in critical processes such as iron homeostasis and mitochondrial integrity
Partial inhibition of the overactivated Ku80-dependent DNA repair pathway rescues neurodegeneration in C9ORF72-ALS/FTD
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