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Jan 12, 2026 The mitochondrial origin of MOTS-c distinguishes it from traditional synthetic peptides, representing an endogenous signaling molecule that declines with age and metabolic dysfunction, making supplementation a form of restoration rather than pharmacological intervention
GLP-1s have genuinely changed the world of obesity treatment for the better, but some people with severe obesity might be turning down surgery when its likely to be their best course of action, the researchers say
Therefore, its possibly useful administration must be strictly controlled
The thousands of anecdotal human reports suggest similar effects to animal studies, but formal human clinical trials remain lacking
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