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Using a double-blind randomized controlled trial, they recruited 46 participants and assigned them to either a placebo group (16.5 grams of dextrose) or a beta-alanine group (1.5 grams of beta-alanine plus 15 grams of dextrose powder)

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This strategy has been exploited in the long-acting GLP-1RA semaglutide (Novo Nordisk), for instance, which was approved for treatment of T2DM in 2017, and for treatment of obesity in 2021, and has since then become the most prescribed GLP-1RA 92

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F.OliveroM.MartoneT.MaffeA.MaggioraP.StefaniA