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Healthcare providers should optimize management of modifiable risk factors, including blood pressure control, glycemic management, and evaluation and treatment of sleep apnea when suspected, to minimize overall NAION risk regardless of medication choice

Patients should consult their provider and insurance plan to determine actual out-of-pocket costs

The weight lost during treatment was projected to return less than 2 years after discontinuation

Most studies were of the case control design, however, additionally there were two double blinded [64, 65] and one open labelled randomised controlled trial [49], a case series [66] and a case report [54]