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Materials and methods Clinical samples of hepatocellular carcinoma patients Human hepatocellular carcinoma (HCC) cancer tumor tissues and matched adjacent tissues ( n = 20) were collected from Cancer Hospital Affiliated to Harbin Medical University for qRT- PCR, western blot and Eliza assays

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Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation