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In the feces samples, a higher proportion of genera Lactobacillus , Helicobacter , and Allopervotella characterized the CON group, a higher proportion of genera Faecalibaculum characterized the MOD group, a higher proportion of genera Akkermansia , Paludicola , and Defluviitaleaceae_UCG_01 characterized the XYP group

However, the timeline of the emergence of depressive symptoms following the initiation of semaglutide therapy raises concerns about the potential role of the medication in precipitating or exacerbating mood disturbances

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Medical oversight is central to these discussions