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Extracellular loops 1 and 3 and their associated transmembrane regions of the calcitonin receptor-like receptor are needed for CGRP receptor function

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The results of our network and enrichment analyses show that NFKB1 was not only one of the most important hotspots in the CFAS-D network, but also that NF-B (p50p52 unit) and RELA (NF-B p65 unit or transcription factor p65) were the most important transcription factors controlling the network and that the NF-B signaling pathway was one of the most important paths enriched in the network

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