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Most skin types, including oily, dry, sensitive, acne-prone, and combination, tolerate it well when its formulation is correct

(Zhou et al., 2017)

People with documented malabsorption disorders including Crohns disease, celiac disease, or those whove had portions of stomach or small intestine removed need direct delivery

Springer Science & Business Media

decreased TSH, decreased Total T4, and decreased Free T4) Uncommon (0.1% to 1%): Galactorrhea, hypoadrenalism, diabetes insipidus [Ref] Local Very common (10% or more): Injection site pain (13.8%), injection site reactions Common (1% to 10%): Injection site hematoma [Ref] Dermatologic Very common (10% or more): Alopecia (13.2%) Common (1% to 10%): Pruritus, bruise, rash Uncommon (0.1% to 1%): Cellulitis, petechiae, urticaria, basal cell carcinoma [Ref] Musculoskeletal Common (1% to 10%): Joint pain, backache Uncommon (0.1% to 1%): Arthritis, joint effusion, muscle pain, Raynaud's phenomenon [Ref] Psychiatric Common (1% to 10%): Depression Uncommon (0.1% to 1%): Anxiety, paranoia, libido decrease [Ref] Other Very common (10% or more): Fatigue (31.8%), generalized pain (15%) Common (1% to 10%): Weakness Uncommon (0.1% to 1%): Hearing loss, otitis [Ref] Respiratory Very common (10% or more): Upper respiratory tract infection (18.2%), sinusitis (12%) Common (1% to 10%): Cold symptoms, flu symptoms, epistaxis Uncommon (0.1% to 1%): Pneumonia, pulmonary nodule, status asthmaticus [Ref] Renal Uncommon (0.1% to 1%): Increased creatinine kinase [Ref] Hypersensitivity Uncommon (0.1% to 1%): Allergic reaction Frequency not reported : Anaphylactic reaction [Ref] Immunologic Very common (10% or more): Antibodies to octreotide (25%) Ocular Common (1% to 10%): Blurred vision, visual disturbance Uncommon (0.1% to 1%): Increased intraocular pressure [Ref] Genitourinary Common (1% to 10%): Urinary tract infection, pollakiuria Uncommon (0.1% to 1%): Gynecomastia, amenorrhea, polymenorrhea, oligomenorrhea, vaginitis, nephrolithiasis, hematuria [Ref] References 1