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The process starts with the enzymes active site, which contains selenocysteine in many isoforms, reacting with the peroxide to form an intermediate

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References 1.Dunn JE, Link CL, Felson DT, Crincoli MG, Keysor JJ, McKinlay JB

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Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy