The high SOD-like activity of the CuTA nanozyme was supported by the coordination environment around the Cu 2+ ions, which allowed the nanozyme to participate effectively in redox reactions
The relatively high systemic insulin levels counteract the lipolytic effects of the high GH levels in fat and muscle, but they do not reach adequate levels in the portal vein, so the liver remains under the control of GH, which still induces gluconeogenesis, increasing hyperglycemia [33]
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