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[12] [13] Pharmacological options are more limited, with NICE advising caution: Antidepressants : A course of duloxetine, amitriptyline, citalopram, or other antidepressants may be considered after discussion of potential benefits and harms

It is important to note that none of these medications address the underlying conditions that cause thrombosis and all alter hemostatic control of blood clotting, increasing the risk of bleeding with potentially dangerous outcomes

For standard research evaluations, a concentration of 100 mcg to 200 mcg per administration is the benchmark

A 2016 study published in the Journal of the American Academy of Dermatology tested a treatment on a 37-year-old man with poliosis and vitiligo, affecting his left eyebrow

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