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58 Interestingly, the expression of this enzyme does not fulfill an instantaneous snapshot of the blood toxicity, but an average value over a time span of about 2/3 months (corresponding to the mean life of the erythrocyte) as it is exclusively expressed during erythropoiesis

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The results of cell cycle assay showed that knockdown of TXNDC12 lead MIA PaCa-2 cell cycle block in G0/G1 phase, whereas, PANC-1 cells were blocked in G2/M phase (Fig