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Acylcarnitines also play a role in detoxifying acyl-CoA intermediates by temporarily sequestering acyl groups, preventing their accumulation

For comprehensive long-term safety data, see our detailed long-term safety analysis

NVO's leading position in this area will be tough for competitors to displace

However, because tirzepatide works on two different hormone receptors (GLP-1 and GIP), the way the body reacts can be slightly different

Interestingly, while non-fatal events did not significantly differ, oral semaglutide clearly reduced deaths from any cause (HR: 0.51, CI: 0.31 to 0.84) or cardiovascular causes (HR: 0.49, CI: 0.27 to 0.92)