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The conflicting data in some clinical studies may be explained by various factors: [1] most cohort studies lacked individual validation of fractures as primary outcomes, [2] the studies had short follow-up duration and [3] did not consider important risk factors for osteoporosis such as BMD (even though BMD is not a good method for diagnosing osteoporosis in T2DM), and [4] some studies included medications that affect fracture risk, such as corticosteroids or antidepressants

In addition, each serving contains 5g of pure Marine Collagen to offer the highest effective dose

Understanding the evidence and potential interactions is essential before combining berberine with prescribed medications

PMID 31559190

These medications work best when paired with habits you can stick with for the long run