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A controlled trial that included 30 healthy volunteers with normal hearing found 600 mg lipoic acid daily for 10 days prior to experimental noise exposure reduced temporary noise-induced hearing loss better than a single 600 mg dose of lipoic acid one hour before noise exposure or no lipoic acid

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Neuroendocrinology Letters, 25(6), 403-406

Start with doses at the lower end of the dosing range