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If you are not losing weight on semaglutide , the source of your medication is one variable worth examining

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GLP-1 RAs Hold Promising Potential for Reduction of Cardiometabolic Risk Factors additional benefits : Brain: Appetite suppression, nerve protection, and decreased neuroinflammation Heart: Decreased blood pressure (systolic and diastolic), reduced total cholesterol levels, lowered endothelial dysfunction, and increased heart rate Liver: Decreased glucose production Pancreas: Increased insulin secretion, decreased glucagon secretion, B islet cell proliferation GI Tract: Decreased gastric emptying Because these drugs cause weight loss, it is not clear whether the GLP-1 RAs or the weight loss reduces cardiometabolic risks

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Reduced fluid intake, nausea, or vomiting can lead to electrolyte imbalances, including: Sodium Potassium Chloride Electrolyte shifts can worsen fatigue, dizziness, muscle cramps, and kidney stress