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GPX4 can reduce lipid hydrogen peroxide (L-OOH) to nontoxic lipid hydroxyl derivatives (L-OH) in a GSH-dependent manner, so as to interrupt ferroptotic cell death caused by harmful lipid peroxides[31]

Prevents localized tissue hardening and lipohypertrophy

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Atrial fibrillation and type 2 diabetes: Prevalence, etiology, pathophysiology and effect of anti-diabetic therapies

Plant Physiol 116:10291036 Cairns NG, Pasternak M, Wachter A, Cobbett CS, Meyer AJ (2006) Maturation of Arabidopsis seeds is dependent on glutathione biosynthesis within the embryo