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263,264 Key targets of the Wnt/-catenin pathway and its related regulatory mechanisms are shown in Fig

This leads to reduced endothelial barrier tightness and increased BBB paracellular permeability (Toborek et al., 2013

Last, large clinical cohorts should be used to disclose associations between serum/synovial fluid TMAO levels, ferroptosis markers in the joints (e.g., MDA), and OA grading by radiological or pathological behavior

Front Pharmacol 12:661805 Qin G, Sun Y, Guo Y, Song Y (2021) PAX5 activates telomerase activity and proliferation in keloid fibroblasts by transcriptional regulation of SND1, thus promoting keloid growth in burn-injured skin

This refers to the formation of small new blood vessels within the thickened and inflamed tendon