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doi: 10.1016/S0140-6736(23)01163-7

93, n o 9, 41704174 (ISSN 0027-8424 et 1091-6490, PMID 8633035, PMCID PMC39506, DOI 10.1073/pnas.93.9.4170, lire en ligne, consult le Biochemical Pharmacology 47: 21132123, 1994 Annual Reviews of Biochemistry 52: 711760, 1983 Journal of Clinical Epidemiology 47: 10211026, 1994 The Lancet 344: 796798, 1994 Ganesaratnam K

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Key Senomorphic Compounds, Their Mode of Action, and Evidence from Preclinical and Clinical Trials Challenges and Opportunities in Senomorphic Therapy Senomorphic therapy offers a promising approach to mitigating the harmful effects of cellular senescence without eliminating the beneficial functions of senescent cells and thus holds great promise in combating age-related diseases

Edaravone, a synthetic free radical scavenger, showed potential by reducing reperfusion injury markers in a Phase II acute MI clinical trial (Tsujita et al., 2006)