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The read mapping, variant calling and joint variant calling were performed using Sentieons DNASeq pipeline v.201808.03, following the BWA-GATK Best Practice Workflow and using the GRCh38/hg38 reference genome

Kidney effects of Glucagon-Like Peptide 1 (GLP1): from molecular foundations to a pharmacophysiological perspective DOI: 10.1590/2175-8239-JBN-2024-0101pt Graphical Abstract Click to view Abstract GLP1 receptor agonists (GLP1-RAs) are drugs that mimic the effects of the incretin hormone GLP1 and were initially introduced in medicine for the treatment of diabetes in 2005 and for obesity in 2014

To date, TMA and TMNO have mostly been treated as nontoxic substances, but more recently, they have been treated as potentially carcinogenic agents, because of the possibility of their transformation into N-nitrosodimethylamine (NDMA) [57]

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Lancet (2018) 391(10140):260718