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We also note that, while NRS, BRAF-NRS, and FAS have been validated in some disorders, currently there is no single fatigue behavioral instrument that has been validated in both hypothyroidism and CFS

The reasoning holds that controlling acute inflammation through cold therapy reduces the work the peptide must do, allowing it to focus on regenerative functions

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Furthermore, DCs possess the ability to follow chemotactic signals, guiding them to immune-related tissues such as lymph nodes, where they interact with T cells, further underlining their crucial role in regulating immune responses [250]

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