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Minimal responders (~20% of patients): Weight loss of less than 1 kg or no meaningful change

Wu P, Dong Y, Chen J, Guan T, Cao B, Zhang Y, et al

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Dehydration can also worsen common tirzepatide side effects like constipation, which may indirectly affect appetite regulation

The basal serum levels of FSH and luteinizing hormone (LH), anti-Mullerian hormone (AMH), thyroid stimulating hormone (TSH) as well as free testosterone and dehydroepiandrosterone sulphate (DHEAS) concentrations were measured in a venous blood sample collected from all participants on the day 2 or 3 of their menstrual cycle