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Rates of moderate or worse side effects ranged from 14% to 32%, but few people stopped treatment due to adverse events

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You should not use GLP-1 medications if you have: Personal or family history of medullary thyroid cancer Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Previous severe allergic reaction to semaglutide or liraglutide Current pregnancy or planning to become pregnant History of pancreatitis (requires careful evaluation) Severe gastrointestinal disease Additionally, these medications are not typically recommended for patients under 18 years old, though Saxenda has some pediatric approval for adolescents 12 and older with obesity

[DOI] [PubMed] [Google Scholar] 89.Ni Z, Smogorzewski M, Massry SG