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Even so, the FDA noted that it could not rule out a small risk because isolated cases of suicidal thoughts or actions have been reported in people using GLP-1 drugs
Effects of Retatrutide on body composition in people with type 2 diabetes
One of the moderators of the session, Dr
He stressed the need for lasting lifestyle changes, which may involve working with nutritionists or sports therapists to develop healthier routines
These drugs also have low uptake (less than 2% in the USA) due to several factors, including patients reluctance to seek treatment, lack of addiction training among healthcare providers and considerable stigma surrounding AUD and addiction. - Lorenzo Leggio, et al, Nature Medicine, December 2023 Based on the percentage of people in the United States with alcohol use disorder (11% or ~29.5 million) and the number of people who have received medication for alcohol use disorder in the past year (624,000) and the number of people taking GLP-1 drugs (7 percent of American adults or 18 million), we roughly estimate that more than 3 times as many people with AUD have been incidentally prescribed a GLP-1 in the past year than have been prescribed a medication that is FDA indicated for alcohol use disorder (~2 million vs 624,000, and these groups may overlap)
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