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Source: New England Journal of Medicine - SELECT Trial Up to 50% improvement in sleep apnea Studies show significant reduction in apnea-hypopnea index (AHI) with GLP-1 therapy, improving sleep quality and reducing OSA severity

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These observations are concordant with recent immunohistochemical data

Via drainage into the portal circulation, VAT floods the liver with FFAs and inflammatory mediators, exacerbating hepatic IR, promoting dyslipidemia, and stimulating the production of acute-phase proteins like CRP, thereby amplifying the systemic inflammatory burden (38, 54)