Some early research suggests that semaglutide may be associated with a lower likelihood of developing cannabis use disorder compared with other medications, though this observational finding does not prove causation, and more clinical studies are needed
What changed recently: Medicare Part D coverage (2026): CMS negotiated a $245/month price for injectable GLP-1s
The medication works by copying the effects of the hormone called GLP-1, which helps regulate blood sugar levels and reduce appetite
Gradual dose escalation, where the dosage is slowly increased, can help minimize this side effect, allowing the body to adjust more comfortably
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