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GSHmediated bactericidal activity in is proposed through the generation of H 2 O 2 via the autooxidation of GSH (Figure 8)

In addition to suppressing appetite, boosting insulin secretion and slowing stomach emptying, these drugs appear to influence brain pathways involved in food reward and cravings, making them a potential candidate for tackling the loss of control that characterizes binge eating

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We upregulated the expression of GCLC, GSS, or SLC7A11 in VRK2-KD PC cells, and investigated the effects of these genes on cell viability, ROS and GSH levels when provided exogenous ROS ter-tbutyl hydroperoxide (TBHP)

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